3-Bromo-5-(trifluoromethyl)pyridin-2-amine
98%
Reagent
Code: #151311
Alias
3-Bromo-2-amino-5-(trifluoromethyl)pyridine
CAS Number
79456-30-7
science Other reagents with same CAS 79456-30-7
blur_circular Chemical Specifications
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Molecular Information
Weight
241.01 g/mol
Formula
C₆H₄BrF₃N₂
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Registry Numbers
MDL Number
MFCD07375382
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Physical Properties
Melting Point
98-101 °C
Boiling Point
221.7 °C at 760 mmHg
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other biologically active compounds. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for creating analogs with improved potency and selectivity. Commonly employed in cross-coupling reactions to form carbon-nitrogen or carbon-carbon bonds, it supports the construction of complex heterocyclic systems found in drug candidates. Also utilized in agrochemical research for designing novel pesticides and herbicides due to the presence of trifluoromethyl and bromo groups that enhance lipophilicity and metabolic stability.
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