5-(Bromomethyl)-2-(trifluoromethyl)pyridine
98%
Reagent
Code: #150011
CAS Number
108274-33-5
science Other reagents with same CAS 108274-33-5
blur_circular Chemical Specifications
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Molecular Information
Weight
240.02 g/mol
Formula
C₇H₅BrF₃N
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Registry Numbers
MDL Number
MFCD10697684
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Physical Properties
Boiling Point
218.4 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, inert gas storage
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of agrochemicals and bioactive molecules. Its reactive bromomethyl group allows for easy functionalization, making it valuable in cross-coupling reactions and the construction of more complex pyridine-based structures. Commonly employed in medicinal chemistry for modifying lead compounds to enhance potency, metabolic stability, or binding affinity. Also utilized in the preparation of ligands for catalysts and in the development of fluorinated analogs to improve lipophilicity and bioavailability.
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