tert-Butyl (4-formylpyridin-2-yl)carbamate

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Reagent Code: #146367
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CAS Number 304873-65-2

science Other reagents with same CAS 304873-65-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 222.24 g/mol
Formula C₁₁H₁₄N₂O₃
thermostat Physical Properties
Melting Point 125-126°C
inventory_2 Storage & Handling
Storage 2-8°C, inert gas atmosphere

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. The aldehyde group allows for further functionalization through reactions such as reductive amination or Wittig chemistry, enabling the introduction of diverse side chains. The tert-butyloxycarbonyl (Boc) protecting group stabilizes the amine during synthetic transformations and can be readily removed under acidic conditions when needed. Its structure is well-suited for use in medicinal chemistry campaigns targeting pyridine-based scaffolds, which are common in drug discovery due to their favorable pharmacokinetic properties and ability to engage in hydrogen bonding.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿760.00
inventory 100mg
10-20 days ฿1,620.00
inventory 250mg
10-20 days ฿2,140.00
inventory 1g
10-20 days ฿6,720.00

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tert-Butyl (4-formylpyridin-2-yl)carbamate
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Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. The aldehyde group allows for further functionalization through reactions such as reductive amination or Wittig chemistry, enabling the introduction of diverse side chains. The tert-butyloxycarbonyl (Boc) protecting group stabilizes the amine during synthetic transformations and can be readily removed under acidic conditions when needed. Its structure is well-suited for use in medicinal chemistry campaigns targeting pyridine-based scaffolds, which are common in drug discovery due to their favorable pharmacokinetic properties and ability to engage in hydrogen bonding.
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