tert-Butyl (4-formylpyridin-2-yl)carbamate
98%
Reagent
Code: #146367
CAS Number
304873-65-2
science Other reagents with same CAS 304873-65-2
blur_circular Chemical Specifications
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Molecular Information
Weight
222.24 g/mol
Formula
C₁₁H₁₄N₂O₃
thermostat
Physical Properties
Melting Point
125-126°C
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Storage & Handling
Storage
2-8°C, inert gas atmosphere
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. The aldehyde group allows for further functionalization through reactions such as reductive amination or Wittig chemistry, enabling the introduction of diverse side chains. The tert-butyloxycarbonyl (Boc) protecting group stabilizes the amine during synthetic transformations and can be readily removed under acidic conditions when needed. Its structure is well-suited for use in medicinal chemistry campaigns targeting pyridine-based scaffolds, which are common in drug discovery due to their favorable pharmacokinetic properties and ability to engage in hydrogen bonding.
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