tert-Butyl (5-iodopyridin-3-yl)carbamate
97%
Reagent
Code: #146098
CAS Number
857266-59-2
science Other reagents with same CAS 857266-59-2
blur_circular Chemical Specifications
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Molecular Information
Weight
320.13 g/mol
Formula
C₁₀H₁₃IN₂O₂
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Registry Numbers
MDL Number
MFCD12407799
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. The iodopyridine moiety allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations, enabling the construction of complex heterocyclic systems. The tert-butyl carbamate (Boc) group serves as a protected amine, offering stability during synthetic transformations and easy deprotection under mild acidic conditions when needed. Commonly employed in medicinal chemistry for lead optimization in drug discovery programs targeting oncology and inflammatory diseases.
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