3-(Benzyloxy)-5-bromopyridine
98%
Reagent
Code: #145477
CAS Number
130722-95-1
science Other reagents with same CAS 130722-95-1
blur_circular Chemical Specifications
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Molecular Information
Weight
264.12 g/mol
Formula
C₁₂H₁₀BrNO
thermostat
Physical Properties
Boiling Point
343.7°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules and drug candidates. Its structure allows for selective functionalization, making it valuable in constructing complex heterocyclic compounds. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to introduce aryl or amino groups. Also utilized in the preparation of kinase inhibitors and central nervous system agents. The bromine moiety serves as a handle for further derivatization, while the benzyloxy group can be deprotected to yield phenolic intermediates for additional modifications.
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