2-(Benzyloxy)-5-bromopyridine
97%
Reagent
Code: #145429
CAS Number
83664-33-9
science Other reagents with same CAS 83664-33-9
blur_circular Chemical Specifications
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Molecular Information
Weight
264.12 g/mol
Formula
C₁₂H₁₀BrNO
thermostat
Physical Properties
Melting Point
45-48°C
Boiling Point
331.2°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other biologically active compounds. Its bromine functionality allows for cross-coupling reactions, enabling the introduction of various substituents through palladium-catalyzed reactions like Suzuki or Heck couplings. The benzyl-protected hydroxyl group can be selectively deprotected to yield a phenolic compound, useful in further derivatization steps. Commonly employed in medicinal chemistry for constructing complex pyridine-based scaffolds found in drug candidates.
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