5-Bromo-2-ethynylpyridine
98%
Reagent
Code: #145014
CAS Number
111770-86-6
science Other reagents with same CAS 111770-86-6
blur_circular Chemical Specifications
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Molecular Information
Weight
182.02 g/mol
Formula
C₇H₄BrN
thermostat
Physical Properties
Melting Point
84-86°C
Boiling Point
212.1°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other biologically active compounds. Its structure allows for selective cross-coupling reactions, making it valuable in constructing complex molecules in medicinal chemistry. Commonly employed in palladium-catalyzed reactions such as Sonogashira coupling to introduce the ethynyl group into target molecules. Also utilized in agrochemical research for designing novel pesticides and herbicides due to its ability to enhance binding affinity and metabolic stability in active ingredients.
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