4-(Boc-amino)-3-iodopyridine
98%
Reagent
Code: #143497
CAS Number
211029-67-3
science Other reagents with same CAS 211029-67-3
blur_circular Chemical Specifications
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Molecular Information
Weight
320.13 g/mol
Formula
C₁₀H₁₃IN₂O₂
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Registry Numbers
MDL Number
MFCD04973409
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Physical Properties
Melting Point
79-83 °C
Boiling Point
313.2±27.0 °C(Predicted)
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Storage & Handling
Density
1.652±0.06 g/cm3(Predicted)
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. The iodine atom allows for further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, enabling the construction of complex pyridine-based structures. The Boc-protected amine group provides stability during reactions and can be selectively deprotected to introduce amine functionality when needed. Commonly employed in medicinal chemistry for lead optimization and in the preparation of drug candidates targeting cancer and inflammatory diseases.
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