4-Fluoro-2-iodopyridine
97%
Reagent
Code: #132176
CAS Number
2385268-22-2
blur_circular Chemical Specifications
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Molecular Information
Weight
222.99 g/mol
Formula
C₅H₃FIN
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Registry Numbers
MDL Number
MFCD31728216
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Physical Properties
Boiling Point
212.0±20.0 °C(Predicted)
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Storage & Handling
Density
2.046±0.06 g/cm3(Predicted)
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for building complex heterocyclic compounds. Commonly employed in Suzuki and Buchwald–Hartwig reactions to introduce the pyridine moiety into drug candidates. Also utilized in the preparation of radiolabeled compounds for positron emission tomography (PET) imaging due to the presence of iodine, which can be substituted with radioactive isotopes.
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