4-Iodo-2-methoxy-5-(trifluoromethyl)pyridine
95%
science Other reagents with same CAS 1227577-09-4
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description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors, antimicrobials, anti-inflammatories, and other biologically active compounds. Its structure enables selective cross-coupling reactions, such as Suzuki, Buchwald–Hartwig, and Heck reactions, making it valuable in medicinal chemistry for constructing complex molecules by introducing the pyridine moiety into target compounds. The iodine substituent facilitates these palladium-catalyzed couplings and supports radiolabeling applications in drug discovery and imaging studies. The methoxy and trifluoromethyl groups modulate electronic properties and enhance solubility in organic solvents, making it suitable for multi-step syntheses. It is also utilized in agrochemical research for designing new active ingredients with improved stability and efficacy.
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