4-Iodo-2-methoxy-5-(trifluoromethyl)pyridine

95%

Reagent Code: #131695
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CAS Number 1227577-09-4

science Other reagents with same CAS 1227577-09-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 303.02 g/mol
Formula C₇H₅F₃INO
badge Registry Numbers
MDL Number MFCD11043681
inventory_2 Storage & Handling
Storage 2-8°C, light-proof, inert gas

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors, antimicrobials, anti-inflammatories, and other biologically active compounds. Its structure enables selective cross-coupling reactions, such as Suzuki, Buchwald–Hartwig, and Heck reactions, making it valuable in medicinal chemistry for constructing complex molecules by introducing the pyridine moiety into target compounds. The iodine substituent facilitates these palladium-catalyzed couplings and supports radiolabeling applications in drug discovery and imaging studies. The methoxy and trifluoromethyl groups modulate electronic properties and enhance solubility in organic solvents, making it suitable for multi-step syntheses. It is also utilized in agrochemical research for designing new active ingredients with improved stability and efficacy.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿7,240.00
inventory 1g
10-20 days ฿21,170.00
inventory 100mg
10-20 days ฿4,270.00

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4-Iodo-2-methoxy-5-(trifluoromethyl)pyridine
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors, antimicrobials, anti-inflammatories, and other biologically active compounds. Its structure enables selective cross-coupling reactions, such as Suzuki, Buchwald–Hartwig, and Heck reactions, making it valuable in medicinal chemistry for constructing complex molecules by introducing the pyridine moiety into target compounds. The iodine substituent facilitates these palladium-catalyzed coupl

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors, antimicrobials, anti-inflammatories, and other biologically active compounds. Its structure enables selective cross-coupling reactions, such as Suzuki, Buchwald–Hartwig, and Heck reactions, making it valuable in medicinal chemistry for constructing complex molecules by introducing the pyridine moiety into target compounds. The iodine substituent facilitates these palladium-catalyzed couplings and supports radiolabeling applications in drug discovery and imaging studies. The methoxy and trifluoromethyl groups modulate electronic properties and enhance solubility in organic solvents, making it suitable for multi-step syntheses. It is also utilized in agrochemical research for designing new active ingredients with improved stability and efficacy.

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