tert-Butyl 6-(hydroxymethyl)picolinate

95%

Reagent Code: #131470
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CAS Number 868769-75-9

science Other reagents with same CAS 868769-75-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 209.24 g/mol
Formula C₁₁H₁₅NO₃
badge Registry Numbers
MDL Number MFCD30737799
thermostat Physical Properties
Boiling Point 346.0±32.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.137±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for building complex heterocyclic systems. The tert-butyl ester acts as a protecting group for the carboxylic acid, providing stability during multi-step syntheses and enabling easy deprotection in the final stages. Commonly employed in research settings to prepare analogs for drug discovery programs, especially in oncology and inflammatory disease targets. Also utilized in the preparation of prodrugs due to the presence of the hydroxymethyl group, which can be modified for improved solubility or metabolic stability.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿8,150.00
inventory 250mg
10-20 days ฿13,850.00

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tert-Butyl 6-(hydroxymethyl)picolinate
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for building complex heterocyclic systems. The tert-butyl ester acts as a protecting group for the carboxylic acid, providing stability during multi-step syntheses and enabling easy deprotection in the final stages. Commonly employed in research settings t

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for building complex heterocyclic systems. The tert-butyl ester acts as a protecting group for the carboxylic acid, providing stability during multi-step syntheses and enabling easy deprotection in the final stages. Commonly employed in research settings to prepare analogs for drug discovery programs, especially in oncology and inflammatory disease targets. Also utilized in the preparation of prodrugs due to the presence of the hydroxymethyl group, which can be modified for improved solubility or metabolic stability.

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