Used in organic synthesis as an intermediate for pharmaceuticals and agrochemicals, particularly in the preparation of nicotinic acid derivatives. Its iodine functionality allows for cross-coupling reactions, such as Suzuki or Heck reactions, enabling the construction of complex heterocyclic systems. Commonly employed in medicinal chemistry for modifying pyridine-based scaffolds to enhance biological activity or binding properties. Also utilized in the development of kinase inhibitors and other bioactive molecules due to the electron-withdrawing ester group and the reactive iodine handle.