tert-Butyl 4-bromopicolinate is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It serves as a key building block in the preparation of complex molecules, often through coupling reactions like Suzuki-Miyaura or Buchwald-Hartwig reactions, which are essential in drug discovery. Additionally, it is utilized in the synthesis of heterocyclic compounds, which are important in creating bioactive molecules with potential therapeutic applications. Its bromine substituent makes it a versatile reagent for further functionalization, enabling the construction of diverse chemical structures.