ethyl 3-(3-ethoxy-4-methoxyphenyl)-2,2-difluorocyclopropane-1-carboxylate
86%
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Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of fluorinated analogs of bioactive molecules. Its structure, featuring a difluorocyclopropane ring, supports enhanced metabolic stability and membrane permeability, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in research settings to explore structure-activity relationships in central nervous system agents and anti-inflammatory compounds. Additionally, it serves as a versatile intermediate in asymmetric chemical reactions to generate chiral derivatives with precise stereocontrol, crucial for modulating drug efficacy at the molecular level. Also utilized in agrochemical research for designing novel pesticides with improved environmental persistence and target specificity.
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