2-Bromo-4-(1,1-difluoroethyl)pyridine
95%
Reagent
Code: #152443
CAS Number
1419221-58-1
blur_circular Chemical Specifications
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Molecular Information
Weight
222.03 g/mol
Formula
C₇H₆BrF₂N
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Registry Numbers
MDL Number
MFCD28559109
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Physical Properties
Boiling Point
234.3±35.0 °C(Predicted)
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Storage & Handling
Density
1.548±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of agrochemicals and bioactive molecules. Its structure allows for selective functionalization in cross-coupling reactions, making it valuable in building complex pyridine-based compounds. Commonly employed in Suzuki and Negishi reactions to introduce the difluoroethylpyridine moiety, which can enhance metabolic stability and lipophilicity in drug candidates. Also utilized in research for creating novel pesticides due to the electron-withdrawing nature of the fluorinated group combined with the pyridine ring’s reactivity.
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