Tert-Butyl (4-(4-Amino-3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidin-1-Yl)Butyl)Carbamate
95%
Reagent
Code: #243860
CAS Number
1887095-79-5
blur_circular Chemical Specifications
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Molecular Information
Weight
432.26 g/mol
Formula
C₁₄H₂₁IN₆O₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a protected intermediate in the synthesis of kinase inhibitors. The tert-butyl carbamate (Boc) group stabilizes the amine during peptide or heterocycle assembly, allowing selective modification of the pyrazolopyrimidine core. Commonly employed in the development of targeted cancer therapies, particularly those involving tyrosine kinase or JAK-STAT pathway inhibition. The iodine substituent enables further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, facilitating structure-activity relationship (SAR) studies. Its solubility and stability profile make it suitable for in vitro assays and early-stage drug screening.
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