4-(4-(8-Oxa-3-Azabicyclo[3.2.1]Octan-3-Yl)-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Aniline
98%
Reagent
Code: #222337
CAS Number
1144068-84-7
blur_circular Chemical Specifications
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Molecular Information
Weight
462.54 g/mol
Formula
C₂₅H₃₀N₆O₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Shows potential in developing treatments for solid tumors due to its ability to cross cell membranes and bind effectively to target enzymes. Also utilized in the design of PROTACs (proteolysis-targeting chimeras) for targeted protein degradation in oncology and inflammatory diseases. Its spirocyclic and heterocyclic structure enhances metabolic stability and bioavailability in preclinical drug candidates.
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