5,7-Dichloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine
97%
Reagent
Code: #180209
CAS Number
939979-32-5
blur_circular Chemical Specifications
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Molecular Information
Weight
203.03 g/mol
Formula
C₆H₄Cl₂N₄
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Registry Numbers
MDL Number
MFCD14584722
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Physical Properties
Boiling Point
397.7±37.0 °C at 760 mmHg
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Storage & Handling
Storage
-20°C, Sealed, Dry
description Product Description
Used as a key intermediate in the synthesis of phosphodiesterase inhibitors, particularly PDE5 inhibitors, which are important in the treatment of erectile dysfunction and pulmonary arterial hypertension. It serves as a building block in medicinal chemistry for developing compounds with high selectivity and potency. Its structure allows for functionalization at multiple sites, enabling the creation of diverse analogs for structure-activity relationship studies. Commonly employed in research and development of new therapeutic agents targeting cyclic nucleotide pathways.
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