5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one

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Reagent Code: #156691
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CAS Number 1211533-31-1

science Other reagents with same CAS 1211533-31-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 184.58 g/mol
Formula C₆H₅ClN₄O
badge Registry Numbers
MDL Number MFCD26959092
thermostat Physical Properties
Boiling Point 377.4±34.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.79±0.1 g/cm3(Predicted)
Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of phosphodiesterase inhibitors, particularly PDE5 inhibitors, which are important in the treatment of erectile dysfunction and pulmonary arterial hypertension. It serves as a building block in the development of active pharmaceutical ingredients due to its ability to form selective, high-affinity interactions with enzyme targets. Its structure allows for functionalization at multiple sites, enabling optimization of pharmacokinetic and pharmacodynamic properties in drug design. Commonly employed in medicinal chemistry for structure-activity relationship studies aimed at improving potency and selectivity of therapeutic agents.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿12,900.00
inventory 500mg
10-20 days ฿29,870.00

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5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
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Used as a key intermediate in the synthesis of phosphodiesterase inhibitors, particularly PDE5 inhibitors, which are important in the treatment of erectile dysfunction and pulmonary arterial hypertension. It serves as a building block in the development of active pharmaceutical ingredients due to its ability to form selective, high-affinity interactions with enzyme targets. Its structure allows for functionalization at multiple sites, enabling optimization of pharmacokinetic and pharmacodynamic properties in drug design. Commonly employed in medicinal chemistry for structure-activity relationship studies aimed at improving potency and selectivity of therapeutic agents.
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