5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
97%
Reagent
Code: #156691
CAS Number
1211533-31-1
blur_circular Chemical Specifications
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Molecular Information
Weight
184.58 g/mol
Formula
C₆H₅ClN₄O
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Registry Numbers
MDL Number
MFCD26959092
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Physical Properties
Boiling Point
377.4±34.0 °C(Predicted)
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Storage & Handling
Density
1.79±0.1 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of phosphodiesterase inhibitors, particularly PDE5 inhibitors, which are important in the treatment of erectile dysfunction and pulmonary arterial hypertension. It serves as a building block in the development of active pharmaceutical ingredients due to its ability to form selective, high-affinity interactions with enzyme targets. Its structure allows for functionalization at multiple sites, enabling optimization of pharmacokinetic and pharmacodynamic properties in drug design. Commonly employed in medicinal chemistry for structure-activity relationship studies aimed at improving potency and selectivity of therapeutic agents.
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