1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride

98%

Reagent Code: #187830
label
Alias Vili watermelon intermediate; Vilisigua intermediate; Vilisigua intermediate; Leosigua intermediate
fingerprint
CAS Number 256499-19-1

science Other reagents with same CAS 256499-19-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 305.74 g/mol
Formula C₁₄H₁₃ClFN₅
badge Registry Numbers
MDL Number MFCD18432772
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting JAK (Janus kinase) and other tyrosine kinases involved in inflammatory and autoimmune diseases. Exhibits potential in the development of treatments for conditions such as rheumatoid arthritis, psoriasis, and certain cancers due to its role in modulating signaling pathways. Its structure allows for high selectivity and binding affinity to enzyme active sites, making it valuable in optimizing drug candidates for improved efficacy and reduced off-target effects. Also employed in structure-activity relationship (SAR) studies to enhance metabolic stability and solubility of related compounds.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿870.00
inventory 5g
10-20 days ฿2,980.00
inventory 25g
10-20 days ฿11,200.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride
No image available
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly those targeting JAK (Janus kinase) and other tyrosine kinases involved in inflammatory and autoimmune diseases. Exhibits potential in the development of treatments for conditions such as rheumatoid arthritis, psoriasis, and certain cancers due to its role in modulating signaling pathways. Its structure allows for high selectivity and binding affinity to enzyme active sites, making it valuable in optimizing drug candidates for improved efficacy and reduced off-target effects. Also employed in structure-activity relationship (SAR) studies to enhance metabolic stability and solubility of related compounds.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...