Di-Tert-Butyl Pyrazolidine-1,2-Dicarboxylate
97%
Reagent
Code: #173877
CAS Number
146605-64-3
blur_circular Chemical Specifications
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Molecular Information
Weight
272.35 g/mol
Formula
C₁₃H₂₄N₂O₄
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Registry Numbers
MDL Number
MFCD16620914
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a chiral auxiliary and asymmetric synthesis reagent in organic chemistry, particularly in enantioselective transformations. Its rigid pyrazolidine core and bulky tert-butyl groups help control stereochemistry during carbon-carbon bond formation. Commonly employed in aldol reactions, alkylations, and Diels-Alder reactions to achieve high diastereoselectivity. After serving its stereodirecting role, the auxiliary can be cleaved under mild hydrolytic or reductive conditions, leaving the desired chiral product intact. Also utilized in pharmaceutical research for the synthesis of optically active intermediates.
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