1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-3-amine

≥95%

Reagent Code: #242790
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CAS Number 885325-91-7

science Other reagents with same CAS 885325-91-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 213.35 g/mol
Formula C₉H₁₉N₃OSi
badge Registry Numbers
MDL Number MFCD24623294
inventory_2 Storage & Handling
Storage 2-8°C, away from light, dry, sealed

description Product Description

Used as a key intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active pyrazole derivatives. This compound features a 1H-pyrazol-3-amine core with the pyrazole nitrogen protected by a (2-(trimethylsilyl)ethoxy)methyl (SEM) group, while the amine at the 3-position remains free for further functionalization. The SEM protecting group allows for selective deprotection under mild acidic conditions, enabling stepwise synthesis in sensitive multi-step reactions. Its heterocyclic structure makes it valuable in constructing complex drug molecules, especially in the development of kinase inhibitors and anti-inflammatory agents. Commonly employed in research settings for medicinal chemistry and drug discovery programs targeting central nervous system disorders and oncology.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿14,800.00

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1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-3-amine
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Used as a key intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active pyrazole derivatives. This compound features a 1H-pyrazol-3-amine core with the pyrazole nitrogen protected by a (2-(trimethylsilyl)ethoxy)methyl (SEM) group, while the amine at the 3-position remains free for further functionalization. The SEM protecting group allows for selective deprotection under mild acidic conditions, enabling stepwise synthesis in sensitive multi-step reactions. Its heter

Used as a key intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active pyrazole derivatives. This compound features a 1H-pyrazol-3-amine core with the pyrazole nitrogen protected by a (2-(trimethylsilyl)ethoxy)methyl (SEM) group, while the amine at the 3-position remains free for further functionalization. The SEM protecting group allows for selective deprotection under mild acidic conditions, enabling stepwise synthesis in sensitive multi-step reactions. Its heterocyclic structure makes it valuable in constructing complex drug molecules, especially in the development of kinase inhibitors and anti-inflammatory agents. Commonly employed in research settings for medicinal chemistry and drug discovery programs targeting central nervous system disorders and oncology.

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