4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole

97%

Reagent Code: #242026
fingerprint
CAS Number 1049730-42-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 276.06 g/mol
Formula C₁₁H₁₆BF₃N₂O₂
badge Registry Numbers
MDL Number MFCD18383264
inventory_2 Storage & Handling
Storage 2-8°C, inert atmosphere

description Product Description

Widely used in cross-coupling reactions, this compound serves as a key boronic ester reagent in Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its pyrazole core is common in bioactive molecules, making it valuable for constructing drug-like structures. The trifluoroethyl group enhances metabolic stability and lipophilicity, which is beneficial in medicinal chemistry for improving pharmacokinetic properties. It is particularly useful in the development of kinase inhibitors and other targeted therapies. Additionally, its boronate functionality allows for rapid diversification through late-stage functionalization in compound libraries for high-throughput screening.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,060.00
inventory 1g
10-20 days ฿3,060.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB