1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole

98%

Reagent Code: #209768
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CAS Number 1025719-23-6

science Other reagents with same CAS 1025719-23-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 276.06 g/mol
Formula C₁₁H₁₆BF₃N₂O₂
badge Registry Numbers
MDL Number MFCD12022323
thermostat Physical Properties
Melting Point 66-67°C
inventory_2 Storage & Handling
Storage -20°C, sealed, dry

description Product Description

Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in medicinal chemistry for constructing complex molecules. The presence of trifluoromethyl and methyl groups enhances electronic and metabolic stability in target compounds, often improving bioavailability and biological activity. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where increased lipophilicity and resistance to oxidative degradation are required.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿960.00
inventory 1g
10-20 days ฿2,400.00
inventory 5g
10-20 days ฿9,590.00
inventory 10g
10-20 days ฿18,800.00
inventory 25g
10-20 days ฿47,000.00

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1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole
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Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in medicinal chemistry for constructing complex molecules. The presence of trifluoromethyl and methyl groups enhances electronic and metabolic stability in target compounds, often improving

Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in medicinal chemistry for constructing complex molecules. The presence of trifluoromethyl and methyl groups enhances electronic and metabolic stability in target compounds, often improving bioavailability and biological activity. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where increased lipophilicity and resistance to oxidative degradation are required.

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