1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole
98%
science Other reagents with same CAS 1025719-23-6
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description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in medicinal chemistry for constructing complex molecules. The presence of trifluoromethyl and methyl groups enhances electronic and metabolic stability in target compounds, often improving bioavailability and biological activity. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where increased lipophilicity and resistance to oxidative degradation are required.
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