5-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
98%
science Other reagents with same CAS 1311197-82-6
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description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. The tetrahydropyranyl (THP) group acts as a protecting group for the pyrazole nitrogen, enabling selective functionalization at the 5-iodo position and facilitating multi-step syntheses. This structure makes it valuable in medicinal chemistry for creating targeted drug candidates. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions to build complex heterocyclic systems. Additionally, the iodine substituent allows for replacement with radioactive isotopes, making it suitable for labeling and tracer studies in research settings for imaging purposes.
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