Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. The tetrahydropyran-2-yl (THP) group acts as a protecting moiety for the pyrazole nitrogen, allowing selective functionalization at the iodo position while preventing unwanted side reactions; it can be easily removed post-synthesis. This structure makes it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki, Heck, Sonogashira, or Stille to introduce the pyrazole moiety into target molecules. Also utilized in agrochemical research for designing new active ingredients with improved stability and activity.