1-(methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
98%
Reagent
Code: #194278
CAS Number
944994-03-0
science Other reagents with same CAS 944994-03-0
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Molecular Information
Weight
272.13 g/mol
Formula
C₁₀H₁₇BN₂O₄S
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Registry Numbers
MDL Number
MFCD18383275
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex nitrogen-containing heterocycles found in bioactive molecules. Due to the methylsulfonyl group's electron-withdrawing properties, it enhances the stability and reactivity profile in such transformations. It is especially useful in medicinal chemistry for rapid diversification of pyrazole-based scaffolds.
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