1-(methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

98%

Reagent Code: #194278
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CAS Number 944994-03-0

science Other reagents with same CAS 944994-03-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 272.13 g/mol
Formula C₁₀H₁₇BN₂O₄S
badge Registry Numbers
MDL Number MFCD18383275
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex nitrogen-containing heterocycles found in bioactive molecules. Due to the methylsulfonyl group's electron-withdrawing properties, it enhances the stability and reactivity profile in such transformations. It is especially useful in medicinal chemistry for rapid diversification of pyrazole-based scaffolds.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,240.00
inventory 250mg
10-20 days ฿2,050.00
inventory 1g
10-20 days ฿5,460.00
inventory 5g
10-20 days ฿20,680.00

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1-(methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
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Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex nitrogen-containing heterocycles found in bioactive molecules. Due to the methylsulfonyl group's electron-withdrawing properties, it enhances the stability and reactivity profile in such transformations. It is especially useful in medicinal chemistry for rapid diversification of pyrazole-based scaffolds.
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