1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-4-carbonitrile

98%

Reagent Code: #192942
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CAS Number 1638360-07-2

science Other reagents with same CAS 1638360-07-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 233.07 g/mol
Formula C₁₁H₁₆BN₃O₂
badge Registry Numbers
MDL Number MFCD22689250
thermostat Physical Properties
Boiling Point 385.7±27.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.11±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in medicinal chemistry for constructing biaryl or heteroaryl frameworks. The nitrile and methyl-substituted pyrazole moieties enhance binding selectivity in bioactive molecules, particularly in kinase inhibitors and anti-inflammatory agents. Commonly employed in late-stage functionalization due to its stability and reactivity under mild conditions.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿14,340.00
inventory 250mg
10-20 days ฿20,480.00
inventory 1g
10-20 days ฿41,440.00

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1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-4-carbonitrile
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in medicinal chemistry for constructing biaryl or heteroaryl frameworks. The nitrile and methyl-substituted pyrazole moieties enhance binding selectivity in bioactive molecules, particularly in kinase inhibitors and anti-inflammatory agents. Commonly employed in late-stage functionalization due to its stability and reactivity under mild conditions.
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