(1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)boronic acid
98%
Reagent
Code: #192874
CAS Number
719296-53-4
science Other reagents with same CAS 719296-53-4
blur_circular Chemical Specifications
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Molecular Information
Weight
242.16 g/mol
Formula
C₉H₁₉BN₂O₃Si
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Registry Numbers
MDL Number
MFCD31802301
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Physical Properties
Boiling Point
363.6±50.0 °C(Predicted)
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Storage & Handling
Density
1.06±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical synthesis. Its boronic acid group facilitates coupling with aryl or vinyl halides under palladium catalysis, making it valuable in constructing complex organic molecules, especially in drug discovery and development. The trimethylsilyl-protected hydroxymethyl group enhances stability and solubility during reaction processes, allowing for selective deprotection when needed. Commonly applied in the synthesis of bioactive pyrazole derivatives with potential therapeutic activity.
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