(1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)boronic acid

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Reagent Code: #192874
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CAS Number 719296-53-4

science Other reagents with same CAS 719296-53-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 242.16 g/mol
Formula C₉H₁₉BN₂O₃Si
badge Registry Numbers
MDL Number MFCD31802301
thermostat Physical Properties
Boiling Point 363.6±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.06±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical synthesis. Its boronic acid group facilitates coupling with aryl or vinyl halides under palladium catalysis, making it valuable in constructing complex organic molecules, especially in drug discovery and development. The trimethylsilyl-protected hydroxymethyl group enhances stability and solubility during reaction processes, allowing for selective deprotection when needed. Commonly applied in the synthesis of bioactive pyrazole derivatives with potential therapeutic activity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,900.00
inventory 250mg
10-20 days ฿4,990.00
inventory 1g
10-20 days ฿13,300.00

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(1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-yl)boronic acid
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical synthesis. Its boronic acid group facilitates coupling with aryl or vinyl halides under palladium catalysis, making it valuable in constructing complex organic molecules, especially in drug discovery and development. The trimethylsilyl-protected hydroxymethyl group enhances stability and solubility during reaction processes, allowing for selective deprotection when needed. Commonly applied in the synthesis of bioactive pyrazole derivatives with potential therapeutic activity.
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