1-(2,2-Difluoroethyl)-1H-pyrazol-3-amine
≥97%
Reagent
Code: #177287
CAS Number
1006462-38-9
blur_circular Chemical Specifications
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Molecular Information
Weight
147.13 g/mol
Formula
C₅H₇F₂N₃
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Registry Numbers
MDL Number
MFCD08696542
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Storage & Handling
Storage
2-8°C, avoid light, inert gas storage
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly kinase inhibitors for cancer treatment. Its pyrazole core and difluoroethyl substituent facilitate binding to enzyme active sites, enhancing selectivity, potency, and metabolic stability. The difluoroethyl group increases lipophilicity and resistance to oxidative degradation, optimizing drug candidates. Also utilized in agrochemical development to improve bioavailability and efficacy of pesticides and herbicides.
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