tert-Butyl 1H-pyrazole-1-carboxylate
95%
Reagent
Code: #144976
CAS Number
219580-32-2
science Other reagents with same CAS 219580-32-2
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Molecular Information
Weight
168.19 g/mol
Formula
C₈H₁₂N₂O₂
thermostat
Physical Properties
Boiling Point
161°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a protecting group for the pyrazole nitrogen in organic synthesis, particularly in pharmaceutical and agrochemical manufacturing. The tert-butoxycarbonyl (Boc) group stabilizes the pyrazole ring during multi-step reactions, allowing selective functionalization at other sites. After the desired transformations, the protecting group is easily removed under mild acidic conditions, regenerating the free pyrazole without degrading the core structure. This makes it valuable in the synthesis of bioactive molecules where pyrazole is a key heterocyclic component.
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