4-Nitro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole

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Reagent Code: #124329
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CAS Number 1260160-79-9

science Other reagents with same CAS 1260160-79-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 243.34 g/mol
Formula C₉H₁₇N₃O₃Si
badge Registry Numbers
MDL Number MFCD25957287
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

This compound is primarily utilized in organic synthesis as a protected intermediate for pyrazole derivatives. Its structure features a nitro group at the 4-position and a ((2-(trimethylsilyl)ethoxy)methyl) (SEM) protecting group on the N1 nitrogen, making it valuable in the development of pharmaceuticals and agrochemicals. The nitro group can be reduced to an amine, enabling further functionalization, while the SEM protecting group can be removed under mild conditions to regenerate the free pyrazole NH functionality. This versatility allows for the creation of complex molecules, particularly in the synthesis of biologically active compounds such as inhibitors or ligands for therapeutic targets. Additionally, its stability and reactivity make it a useful building block in medicinal chemistry research.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿45,630.00
inventory 100mg
10-20 days ฿24,336.00

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4-Nitro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole
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This compound is primarily utilized in organic synthesis as a protected intermediate for pyrazole derivatives. Its structure features a nitro group at the 4-position and a ((2-(trimethylsilyl)ethoxy)methyl) (SEM) protecting group on the N1 nitrogen, making it valuable in the development of pharmaceuticals and agrochemicals. The nitro group can be reduced to an amine, enabling further functionalization, while the SEM protecting group can be removed under mild conditions to regenerate the free pyrazole NH

This compound is primarily utilized in organic synthesis as a protected intermediate for pyrazole derivatives. Its structure features a nitro group at the 4-position and a ((2-(trimethylsilyl)ethoxy)methyl) (SEM) protecting group on the N1 nitrogen, making it valuable in the development of pharmaceuticals and agrochemicals. The nitro group can be reduced to an amine, enabling further functionalization, while the SEM protecting group can be removed under mild conditions to regenerate the free pyrazole NH functionality. This versatility allows for the creation of complex molecules, particularly in the synthesis of biologically active compounds such as inhibitors or ligands for therapeutic targets. Additionally, its stability and reactivity make it a useful building block in medicinal chemistry research.

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