4-Nitro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole
95%
science Other reagents with same CAS 1260160-79-9
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description Product Description
This compound is primarily utilized in organic synthesis as a protected intermediate for pyrazole derivatives. Its structure features a nitro group at the 4-position and a ((2-(trimethylsilyl)ethoxy)methyl) (SEM) protecting group on the N1 nitrogen, making it valuable in the development of pharmaceuticals and agrochemicals. The nitro group can be reduced to an amine, enabling further functionalization, while the SEM protecting group can be removed under mild conditions to regenerate the free pyrazole NH functionality. This versatility allows for the creation of complex molecules, particularly in the synthesis of biologically active compounds such as inhibitors or ligands for therapeutic targets. Additionally, its stability and reactivity make it a useful building block in medicinal chemistry research.
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