Used primarily as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where the pyrazine ring serves as a core scaffold. Its functional groups enable selective substitutions, making it valuable in constructing complex heterocyclic compounds. It is also employed in agrochemical synthesis for creating novel pesticides and herbicides due to its reactivity and ability to enhance molecular diversity. Additionally, it finds use in research laboratories for the preparation of ligands and functionalized materials in medicinal chemistry.