2-Bromo-5-(difluoromethoxy)pyrazine
≥95%
Reagent
Code: #132918
CAS Number
1261768-93-7
science Other reagents with same CAS 1261768-93-7
blur_circular Chemical Specifications
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Molecular Information
Weight
224.99 g/mol
Formula
C₅H₃BrF₂N₂O
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Registry Numbers
MDL Number
MFCD11846435
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in creating bioactive molecules. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to build complex heterocyclic systems. Also utilized in agrochemical research for designing novel pesticides with improved metabolic stability. The difluoromethoxy group enhances lipophilicity and resistance to oxidative degradation, beneficial in optimizing drug candidates.
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