2-Bromo-5-(difluoromethoxy)pyrazine

≥95%

Reagent Code: #132918
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CAS Number 1261768-93-7

science Other reagents with same CAS 1261768-93-7

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scatter_plot Molecular Information
Weight 224.99 g/mol
Formula C₅H₃BrF₂N₂O
badge Registry Numbers
MDL Number MFCD11846435
inventory_2 Storage & Handling
Storage 2-8°C, light-proof, inert gas

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in creating bioactive molecules. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to build complex heterocyclic systems. Also utilized in agrochemical research for designing novel pesticides with improved metabolic stability. The difluoromethoxy group enhances lipophilicity and resistance to oxidative degradation, beneficial in optimizing drug candidates.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿19,070.00
inventory 250mg
10-20 days ฿28,600.00
inventory 1g
10-20 days ฿71,500.00

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2-Bromo-5-(difluoromethoxy)pyrazine
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in creating bioactive molecules. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to build complex heterocyclic systems. Also utilized in agrochemical research for designing novel pesticides with improved metabolic stability. The difluoromethoxy group enhances lipophilicity and resistance to oxidative degradation, beneficial in optimizing drug candidates.
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