Naphyrone hydrochloride is primarily used in research settings to study its effects on the central nervous system. It acts as a stimulant and has been investigated for its interaction with monoamine transporters, particularly dopamine, norepinephrine, and serotonin. Researchers utilize it to understand the pharmacological mechanisms of synthetic cathinones and their potential impact on neurotransmitter systems. Additionally, it has been studied in the context of substance abuse to explore its addictive properties and behavioral effects. Due to its psychoactive nature, it is not approved for medical or therapeutic use and is strictly regulated to prevent misuse.