NEXIUM (esomeprazole magnesium) is primarily used to treat conditions related to excess stomach acid. It is commonly prescribed for managing gastroesophageal reflux disease (GERD), where it helps reduce acid production and alleviates symptoms like heartburn and acid regurgitation. It is also effective in healing erosive esophagitis, a condition where stomach acid damages the esophagus lining. Additionally, it is used in combination with antibiotics to treat Helicobacter pylori infections, which can lead to stomach ulcers. For patients with Zollinger-Ellison syndrome, a rare condition causing excessive stomach acid production, NEXIUM helps control acid levels. It is also utilized in preventing stomach ulcers in individuals taking nonsteroidal anti-inflammatory drugs (NSAIDs) long-term.