Used as a standard in mass spectrometry for calibration and instrument performance verification, particularly in proteomics research. Its well-defined structure and consistent behavior during ionization make it ideal for tuning and validating MALDI-TOF and ESI mass spectrometers. Frequently employed in peptide analysis workflows to ensure accuracy and reproducibility in molecular weight determination. Also utilized in studies involving fibrinogen metabolism and blood coagulation pathways due to its origin from fibrinogen processing.