1-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclopropanol
≥95%
science Other reagents with same CAS 441784-82-3
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description Product Description
This compound is a specialized building block in organic synthesis, featuring a tert-butyldiphenylsilyl (TBDPS)-protected hydroxymethyl group on a cyclopropanol core. The TBDPS protection shields the primary alcohol from unwanted reactions during multi-step processes, offering excellent stability under acidic, basic, and oxidative conditions. The cyclopropanol moiety acts as a reactive synthon, commonly used in ring-opening reactions (e.g., via the semi-pinacol rearrangement or homologation) to assemble complex carbocycles and heterocycles. It is particularly valuable in the total synthesis of pharmaceuticals, natural products, and bioactive molecules, allowing precise control over functional group transformations.
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