This chemical is primarily used as a protecting group reagent in organic synthesis. It is particularly effective in protecting hydroxyl groups during complex multi-step reactions, ensuring that specific functional groups remain unaffected while other transformations occur. The tert-butyldimethylsilyl (TBDMS) group is stable under a variety of reaction conditions, making it a valuable tool in the synthesis of pharmaceuticals, natural products, and other fine chemicals. Additionally, its use in the preparation of intermediates for drug development highlights its importance in medicinal chemistry. The chloro and hydroxyl groups in the molecule also provide sites for further functionalization, enabling the creation of diverse chemical structures.