(9H-Fluoren-9-yl)methyl tert-butyl ethane-1,2-diyldicarbamate
97%
science Other reagents with same CAS 166410-28-2
blur_circular Chemical Specifications
description Product Description
This compound is a protected derivative of ethylenediamine, featuring an Fmoc [(9H-fluoren-9-yl)methoxy]carbonyl group on one amine and a Boc (tert-butoxycarbonyl) group on the other. It serves as a versatile building block and linker in organic synthesis, particularly in solid-phase peptide synthesis (SPPS) and the preparation of bioactive molecules. The orthogonal protecting groups enable selective deprotection: the Fmoc group is stable to acid but removed under mild basic conditions (e.g., piperidine in DMF), while the Boc group is stable to base but cleaved under acidic conditions (e.g., TFA). This selectivity is essential for assembling complex peptide chains or incorporating diamine spacers without side reactions, making it invaluable in pharmaceutical research and development.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White solid |
| Purity (%) | 96.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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