(9H-Fluoren-9-yl)methyl tert-butyl ethane-1,2-diyldicarbamate

97%

Reagent Code: #37154
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CAS Number 166410-28-2

science Other reagents with same CAS 166410-28-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 382.4529 g/mol
Formula C₂₂H₂₆N₂O₄
inventory_2 Storage & Handling
Storage room temperature

description Product Description

This compound is a protected derivative of ethylenediamine, featuring an Fmoc [(9H-fluoren-9-yl)methoxy]carbonyl group on one amine and a Boc (tert-butoxycarbonyl) group on the other. It serves as a versatile building block and linker in organic synthesis, particularly in solid-phase peptide synthesis (SPPS) and the preparation of bioactive molecules. The orthogonal protecting groups enable selective deprotection: the Fmoc group is stable to acid but removed under mild basic conditions (e.g., piperidine in DMF), while the Boc group is stable to base but cleaved under acidic conditions (e.g., TFA). This selectivity is essential for assembling complex peptide chains or incorporating diamine spacers without side reactions, making it invaluable in pharmaceutical research and development.

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Test Parameter Specification
Appearance White solid
Purity (%) 96.5-100%
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,174.00

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(9H-Fluoren-9-yl)methyl tert-butyl ethane-1,2-diyldicarbamate
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This compound is a protected derivative of ethylenediamine, featuring an Fmoc [(9H-fluoren-9-yl)methoxy]carbonyl group on one amine and a Boc (tert-butoxycarbonyl) group on the other. It serves as a versatile building block and linker in organic synthesis, particularly in solid-phase peptide synthesis (SPPS) and the preparation of bioactive molecules. The orthogonal protecting groups enable selective deprotection: the Fmoc group is stable to acid but removed under mild basic conditions (e.g., piperidine

This compound is a protected derivative of ethylenediamine, featuring an Fmoc [(9H-fluoren-9-yl)methoxy]carbonyl group on one amine and a Boc (tert-butoxycarbonyl) group on the other. It serves as a versatile building block and linker in organic synthesis, particularly in solid-phase peptide synthesis (SPPS) and the preparation of bioactive molecules. The orthogonal protecting groups enable selective deprotection: the Fmoc group is stable to acid but removed under mild basic conditions (e.g., piperidine in DMF), while the Boc group is stable to base but cleaved under acidic conditions (e.g., TFA). This selectivity is essential for assembling complex peptide chains or incorporating diamine spacers without side reactions, making it invaluable in pharmaceutical research and development.

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