tert-Butyl (4-acetylphenyl)carbamate is the Boc-protected derivative of 4-aminoacetophenone, serving as a key intermediate in organic synthesis, especially for pharmaceuticals and fine chemicals. The tert-butoxycarbonyl (Boc) group protects the amine, providing stability under acidic and basic conditions, which enables selective functionalization of the acetophenone moiety in multi-step processes. It is commonly used in the synthesis of intermediates for active pharmaceutical ingredients (APIs), allowing orthogonal protection strategies. The acetyl group acts as a versatile precursor for further derivatization, such as reduction to alcohols or conversion to other carbonyl derivatives. In research, it supports studies on enzyme inhibition and receptor binding due to its structural features.