(3-Bromo-4-methylphenoxy)(tert-butyl)dimethylsilane

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Reagent Code: #36687
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CAS Number 164513-48-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 301.30 g/mol
Formula C₁₃H₂₁BrOSi
badge Registry Numbers
MDL Number MFCD24847837
thermostat Physical Properties
Boiling Point 293.6±28.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature, dry and sealed

description Product Description

(3-Bromo-4-methylphenoxy)(tert-butyl)dimethylsilane is a protected derivative of 3-bromo-4-methylphenol, featuring a tert-butyldimethylsilyl (TBDMS) group on the phenolic oxygen. This compound serves as a key intermediate in organic synthesis, enabling selective functionalization of the aromatic ring, such as through palladium-catalyzed cross-coupling reactions at the bromo position, while the hydroxyl group remains masked. It is particularly useful in the multi-step synthesis of pharmaceuticals, agrochemicals, and advanced materials. The TBDMS protecting group provides stability during reactions and can be readily removed under mild acidic or fluoride conditions to afford the free phenol.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿2,052.00
inventory 5g
10-20 days ฿4,104.00
inventory 10g
10-20 days ฿5,868.00

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