Used as a reagent in organic synthesis, particularly in the introduction of the trifluoroacetyl group to amines and alcohols. It serves as a protecting group due to the electron-withdrawing nature of the trifluoroacetyl moiety, which can stabilize intermediates and modify reactivity. Commonly applied in pharmaceutical synthesis where fluorinated compounds enhance metabolic stability and bioavailability. Also employed in the preparation of fluorinated building blocks for agrochemicals and specialty materials. Its volatility and reactivity make it suitable for use in low-temperature acylation reactions.