tert-Butyldimethylsilyl chloride solution

1.0 M in THF

Reagent Code: #142691
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CAS Number 18162-48-6

science Other reagents with same CAS 18162-48-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 150.72 g/mol
Formula C₆H₁₅ClSi
badge Registry Numbers
EC Number 242-042-4
MDL Number MFCD00000501
thermostat Physical Properties
Melting Point 86-89 °C
Boiling Point 125 °C(lit.)
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Widely used in organic synthesis as a silyl protecting group reagent, particularly for alcohols and phenols. It selectively protects hydroxyl groups, enhancing stability during multi-step reactions. Commonly employed in the synthesis of complex molecules like natural products and pharmaceuticals, where protection of polar functional groups is essential. Its bulky structure provides steric hindrance, offering good selectivity and resistance to unwanted deprotection. Stable under a variety of reaction conditions, it allows for compatibility with oxidation, reduction, and coupling reactions. Deprotection is typically achieved under mild acidic conditions or with fluoride sources like TBAF, making it versatile and reliable in synthetic strategies.

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inventory 100ml
10-20 days ฿9,250.00

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tert-Butyldimethylsilyl chloride solution
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Widely used in organic synthesis as a silyl protecting group reagent, particularly for alcohols and phenols. It selectively protects hydroxyl groups, enhancing stability during multi-step reactions. Commonly employed in the synthesis of complex molecules like natural products and pharmaceuticals, where protection of polar functional groups is essential. Its bulky structure provides steric hindrance, offering good selectivity and resistance to unwanted deprotection. Stable under a variety of reaction cond

Widely used in organic synthesis as a silyl protecting group reagent, particularly for alcohols and phenols. It selectively protects hydroxyl groups, enhancing stability during multi-step reactions. Commonly employed in the synthesis of complex molecules like natural products and pharmaceuticals, where protection of polar functional groups is essential. Its bulky structure provides steric hindrance, offering good selectivity and resistance to unwanted deprotection. Stable under a variety of reaction conditions, it allows for compatibility with oxidation, reduction, and coupling reactions. Deprotection is typically achieved under mild acidic conditions or with fluoride sources like TBAF, making it versatile and reliable in synthetic strategies.

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