2-(tert-Butyl)-2-methyl-1,3-dioxolane
97%
science Other reagents with same CAS 6135-54-2
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description Product Description
Used as a protecting group reagent for carbonyl compounds in organic synthesis. It selectively reacts with aldehydes and ketones to form dioxolane derivatives, shielding the carbonyl group during multi-step reactions. This protection is especially useful in complex molecule synthesis, such as in pharmaceuticals and natural products, where sensitive functional groups must remain intact. The tert-butyl and methyl substituents enhance steric stability, making the resulting dioxolane resistant to hydrolysis under mild conditions. Deprotection can be achieved under mild acidic conditions, allowing for controlled release of the original carbonyl compound. Its stability and ease of removal make it valuable in fine chemical and medicinal chemistry applications.
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