2-(tert-Butyl)-2-methyl-1,3-dioxolane

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Reagent Code: #130498
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CAS Number 6135-54-2

science Other reagents with same CAS 6135-54-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 144.21 g/mol
Formula C₈H₁₆O₂
badge Registry Numbers
MDL Number MFCD00030566
thermostat Physical Properties
Boiling Point 58 °C at 27 mmHg
inventory_2 Storage & Handling
Density 0.915 g/cm3 at 30 °C
Storage 2-8°C, sealed, dry

description Product Description

Used as a protecting group reagent for carbonyl compounds in organic synthesis. It selectively reacts with aldehydes and ketones to form dioxolane derivatives, shielding the carbonyl group during multi-step reactions. This protection is especially useful in complex molecule synthesis, such as in pharmaceuticals and natural products, where sensitive functional groups must remain intact. The tert-butyl and methyl substituents enhance steric stability, making the resulting dioxolane resistant to hydrolysis under mild conditions. Deprotection can be achieved under mild acidic conditions, allowing for controlled release of the original carbonyl compound. Its stability and ease of removal make it valuable in fine chemical and medicinal chemistry applications.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿9,600.00
inventory 100mg
10-20 days ฿11,800.00
inventory 250mg
10-20 days ฿19,960.00

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2-(tert-Butyl)-2-methyl-1,3-dioxolane
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Used as a protecting group reagent for carbonyl compounds in organic synthesis. It selectively reacts with aldehydes and ketones to form dioxolane derivatives, shielding the carbonyl group during multi-step reactions. This protection is especially useful in complex molecule synthesis, such as in pharmaceuticals and natural products, where sensitive functional groups must remain intact. The tert-butyl and methyl substituents enhance steric stability, making the resulting dioxolane resistant to hydrolysis

Used as a protecting group reagent for carbonyl compounds in organic synthesis. It selectively reacts with aldehydes and ketones to form dioxolane derivatives, shielding the carbonyl group during multi-step reactions. This protection is especially useful in complex molecule synthesis, such as in pharmaceuticals and natural products, where sensitive functional groups must remain intact. The tert-butyl and methyl substituents enhance steric stability, making the resulting dioxolane resistant to hydrolysis under mild conditions. Deprotection can be achieved under mild acidic conditions, allowing for controlled release of the original carbonyl compound. Its stability and ease of removal make it valuable in fine chemical and medicinal chemistry applications.

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