H-Arg(Pbf)-OH
97%
Reagent
Code: #97579
CAS Number
200115-86-2
blur_circular Chemical Specifications
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Molecular Information
Weight
426.53 g/mol
Formula
C₁₉H₃₀N₄O₅S
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Registry Numbers
MDL Number
MFCD00236797
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Physical Properties
Boiling Point
636.9°C
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Storage & Handling
Storage
room temperature, dry
description Product Description
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of arginine, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain during the synthesis process. This protection is crucial to prevent unwanted side reactions and ensure the correct sequence of amino acids in the peptide chain. After the peptide synthesis is complete, the Pbf group can be removed using standard deprotection methods, such as treatment with trifluoroacetic acid (TFA). This compound is essential for producing high-purity peptides, which are used in various research applications, including drug development, biochemical studies, and the production of therapeutic peptides. Its stability and compatibility with SPPS make it a valuable reagent in the field of peptide chemistry.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | 96.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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