(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid
97%
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description Product Description
This chemical is a protected derivative of N-methyl-L-tryptophan, primarily utilized in solid-phase peptide synthesis (SPPS). The fluorenylmethoxycarbonyl (Fmoc) group protects the N-methyl alpha-amino functionality, while the tert-butoxycarbonyl (Boc) group protects the indole nitrogen of the tryptophan side chain. This dual protection strategy enables selective deprotection during the stepwise assembly of peptides, ensuring process integrity and specificity. It is particularly valuable for synthesizing complex peptides containing N-methylated tryptophan residues, as it minimizes unwanted side reactions, improves yield, and enhances purity. Applications are essential in pharmaceutical research, biotechnology, and the development of peptide-based therapeutics.
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