N-Boc-cis-4-Fluoro-L-proline Methyl Ester

≥97%

Reagent Code: #76510
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CAS Number 203866-16-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 247.26 g/mol
Formula C₁₁H₁₈FNO₄
badge Registry Numbers
MDL Number MFCD11054130
inventory_2 Storage & Handling
Density 1.153(lit.)
Storage room temperature, dry

description Product Description

This compound is primarily utilized in the synthesis of peptides and pharmaceuticals, particularly where the introduction of a fluorine atom is necessary for enhancing biological activity or stability. It serves as a protected form of proline, with the Boc (tert-butoxycarbonyl) group providing temporary protection for the amine functionality and the methyl ester protecting the carboxylic acid, allowing for selective reactions in peptide coupling processes and improved solubility and stability. The Boc group enables controlled deprotection during multi-step synthesis. Its application is significant in the development of drug candidates, especially in the field of medicinal chemistry, where fluorinated amino acids are often incorporated to improve metabolic stability and binding affinity. Additionally, it is used in research to study the effects of fluorination on peptide structure and function.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White to off-white solid
Purity 96.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,480.00
inventory 1g
10-20 days ฿3,780.00
inventory 5g
10-20 days ฿10,210.00

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