N-Boc-4,4-Difluoro-L-proline methyl ester
97%
Reagent
Code: #76494
Alias
(2S)-2-(methoxycarbonyl)-4,4-difluoropyrrolidine-1-carboxylate tert-butyl ester, 1-tert-butyl-2-methyl-(2S)-4,4-difluoro Pyrrolidine-1,2-dicarboxylate
CAS Number
203866-17-5
science Other reagents with same CAS 203866-17-5
blur_circular Chemical Specifications
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Molecular Information
Weight
265.25 g/mol
Formula
C₁₁H₁₇F₂NO₄
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Registry Numbers
MDL Number
MFCD03094918
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Physical Properties
Melting Point
41-46°C
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Storage & Handling
Storage
2~8°C
description Product Description
Used primarily in peptide synthesis, this compound serves as a protected form of 4,4-difluoro-L-proline, enabling the introduction of fluorine atoms into peptides to enhance their stability and biological activity. It is particularly valuable in medicinal chemistry for designing peptide-based drugs with improved metabolic stability and binding affinity. The Boc group ensures selective deprotection during synthesis, while the methyl ester facilitates solubility and handling. Its application is crucial in developing fluorinated peptides for therapeutic and diagnostic purposes.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Off-White Solid |
| Purity (%) | 96.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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