Used in peptide synthesis as a protecting group for cysteine residues, ensuring selective deprotection during the process. It is particularly valuable in solid-phase peptide synthesis (SPPS) due to its stability under standard conditions and ease of removal under mild conditions. The sulfonate group enhances solubility in aqueous solutions, facilitating purification and handling of peptides. This compound is also employed in the study of protein folding and disulfide bond formation, as it allows controlled cysteine reactivity. Additionally, it finds application in the development of peptide-based drugs and biomaterials, where precise cysteine modification is critical for functionality.